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ACT-389949

SKU: orb1310021

Description

ACT-389949

Images & Validation

Key Properties

CAS Number1258417-54-7
MW428.39
Purity99.40%
FormulaC20H18F2N6O3
SMILESCc1nc(C(=O)Nc2cnn(Cc3nc(co3)C(C)(F)F)n2)c(o1)-c1cccc(C)c1
TargetOthers
Solubility10% DMSO+90% Corn Oil:1 mg/mL (2.33 mM);DMSO:10 mg/mL (23.34 mM)

Bioactivity

Target IC50
FPR2/ALX:3 nM(EC50)
In Vivo
ACT-389949 demonstrates a favorable tolerance profile. Peak concentration levels occur approximately 2 hours post-administration, and it exhibits a mean terminal half-life of 29.3 hours. The administration of ACT-389949 induces a dose-dependent, prolonged internalization of FPR2/ALX within leukocytes .

Storage & Handling

StoragePowder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ACT389949, ACT-389949, ACT 389949, FPR2/ALX, Inhibitor, inhibit

Similar Products

  • ACT-389949 [orb1218982]

    >98% (HPLC)

    1258417-54-7

    428.4

    C20H18F2N6O3

    200 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 g, 500 mg
Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

ACT-389949 (orb1310021)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 mg
¥ 1,820.00
5 mg
¥ 2,470.00
10 mg
¥ 3,510.00
25 mg
¥ 5,720.00
50 mg
¥ 8,320.00
100 mg
¥ 12,090.00
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