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Aripiprazole Lauroxil

SKU: orb1308641

Description

Aripiprazole Lauroxil

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1259305-29-7
MW660.71
Purity99.64%
FormulaC36H51Cl2N3O4
SMILESCCCCCCCCCCCC(=O)OCN1C(=O)CCc2ccc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)cc12
TargetDopamine Receptor,Others,5-HT Receptor
SolubilityDMSO:8 mg/mL (12.11 mM);10% DMSO+90% Corn Oil:0.5 mg/mL (0.76 mM)

Bioactivity

In Vivo
Intravenous administration of 1.87 mg/ml Aripiprazole lauroxil bioconversion in vivo involves the formation of an intermediate, N-hydroxymethyl aripiprazole. The in vitro data indicates a high bioconversion of aripiprazole lauroxil, thus, the concentration of N-hydroxymethyl aripiprazole observed in the animals dosed with aripiprazole lauroxil is surprisingly high.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, DopamineReceptor, Dopamine Receptor, D2 receptor, 5HTReceptor, 5HT Receptor, 5-HT1A, 5-HT2A, Aripiprazole Lauroxil, Aristada, schizophrenia
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Key Properties

No computed properties available.

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Protocol Information

Aripiprazole Lauroxil (orb1308641)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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% DMSO +
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% Tween 80 +
%

Available Sizes

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1 ml x 10 mM (in DMSO)
¥ 1,170.00
10 mg
¥ 1,170.00
25 mg
¥ 1,430.00
50 mg
¥ 1,820.00
100 mg
¥ 2,340.00
200 mg
¥ 3,120.00
500 mg
¥ 4,940.00
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