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DODAP

SKU: orb1691847

Description

DODAP

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number127512-29-2
MW648.05
FormulaC41H77NO4
SMILESCCCCCCCC\C=C/CCCCCCCC(=O)OCC(CN(C)C)OC(=O)CCCCCCC\C=C/CCCCCCCC
TargetOthers
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.09 mM);DMSO:80 mg/mL (123.45 mM);Ethanol:80 mg/mL (123.45 mM)

Bioactivity

In Vivo
Mice were injected with DODAP-LNPs (0.5 mg/kg mRNA, 200 μL); after 24 h, luciferase expression was mainly in liver and spleen but lower than MC3-LNPs.
In Vitro
DODAP-based LNPs delivered luciferase mRNA to HEK293T cells for 24 h; luciferase expression was lower than MC3-LNPs, indicating reduced transfection efficiency.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

DODAP

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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5 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 100.00
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