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Description
Research Area
Cardiovascular Research; Musculoskeletal & Connective Tissue Research
Images & Validation
−
Item 1 of 6
| Tested Applications | FC, ICC, IF, IHC-Fr, IHC-P, WB |
|---|---|
| Dilution Range | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, Flow-Cyt=1μg/Test |
| Reactivity | Human |
| Predicted Reactivity | Bovine, Equine, Mouse, Porcine, Rabbit, Rat, Sheep |
Related Conjugates & Formulations
−Key Properties
−| Antibody Type | Primary Antibody |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated synthetic peptide derived from human MMP-2 (401-500/662aa) |
| Target | MMP2 |
| Molecular Weight | 62 kDa |
| Purification | Affinity purified by Protein A |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Form/Appearance | Liquid |
| Buffer/Preservatives | 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Expiration Date | 12 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1; MMP2_HUMAN; MMP2; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2 (MMP-2); 3.4.24.24; matrix metallopeptidase 2; matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
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Quick Database Links
Gene Symbol
MMP2
UniProt
UniProt Details
− No UniProt data available
Protocol Information
WB
Western Blot (IB, immunoblot)
IHC-P
Immunohistochemistry Paraffin
IHC-Fr
Immunohistochemistry Frozen
FC
Flow Cytometry
IF
Immunofluorescence
ICC
Immunocytochemistry
Filter by Applications
Filter by Species
Ayantika Kundu,Pratiti Ghosh, Biswadev Bishayi Vitexin along with verapamil downregulates efflux pump P-glycoprotein in macrophages and potentiate M1 to M2 switching via TLR4-NF-κB-TNFR5 pathway in Lipopolysaccharide treated mice Immunobiology, 229(1), 152767 (2024)
Applications
WB
Reactivity
Mouse
Sahin Sultana, Rajen Dey, Biswadev Bishayi Dual neutralization of TNFR-2 and MMP-2 regulates the severity of S. aureus induced septic arthritis correlating alteration in the level of interferon gamma and interleukin-10 in terms of TNFR2 blocking Immunologic Research, 66, 97 (2018)
Applications
WB
Reactivity
Mouse
Berta H Ganizada 1 2 3, Koen D Reesink 3 4, Shaiv Parikh 3 4, Pepijn J M H Saraber 2 3 4, Jack P Cleutjens 3 5, Austin Isabella 2 3, Mathilde Q E Krebbekx 1 3, Armand M Jaminon 2 3, Cecile F M Maassen 2 3, Mitch J F G Ramaekers 3 6 7, Bart Spronck 3 4, Koen van der Laan 3 4, Rory R Koenen 2 3, Roberto Lorusso 1 3, Jos G Maessen 1 3, Elham Bidar 1 3, Leon J Schurgers Loss of wall stress homoeostasis in ascending thoracic aortic aneurysm: histomorphometric insights into patient variants J Physiol ., (2025)
Applications
IHC
Reactivity
Human
Available Sizes
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