123B9

123B9 is a tumor-homing small molecule that acts as a potent and selective EphA2 agonist (Kd = 4.0 µM), targeting its ligand-binding domain with minimal activity on EphA3/A4. It is a valuable research tool for studying EphA2 receptor signaling in cancer biology, applicable in both in vitro binding assays and in vivo tumor-targeting experiments.