You have no items in your shopping cart.
.png)
Single-domain antibodies (VHH or nanobodies) derived from camelid species (Alpaca/Llama) have gained widespread recognition in biological research and therapeutics due to their compact size (15 kDa), exceptionally high binding affinity, and robust thermal and conformational stability. Our experienced scientific team at Biorbyt is dedicated to delivering high-quality VHH antibodies customized to your unique experimental requirements.
Service Highlights & Advantages
Efficient Single B Platform
Utilizing our proprietary Single B platform, we efficiently isolate and culture antigen-specific B cells directly from immunized camelids, enabling the rapid generation of high-quality nanobodies tailored to your specific targets.
Rapid VHH Library Generation
Within just 4 weeks, we can construct a comprehensive VHH phage display library derived from immunized camelid B cells, serving as a highly diverse resource for identifying exceptional binding candidates.
Accelerated Screening Process
Our optimized high-throughput screening workflows allow for the positive identification of validated VHH hits within 2 months, significantly shortening development timelines compared to traditional hybridoma methods.
Mammalian Display Optimization
Selected nanobody leads can be further refined using our mammalian cell display-based antibody engineering system to enhance affinity, expression yield, or structural stability.
Development Phases & Timeline
Our streamlined contract workflow ensures rapid progression from animal immunization through to validated VHH hit delivery:
| Stage | Service Details | Estimated Turnaround |
|---|---|---|
| 1. Camelid Immunization | Immunization of Alpacas or Llamas to elicit a robust, target-specific immune response against your antigen. | 6 – 8 Weeks |
| 2. Single B Isolation | Precision isolation and enrichment of antigen-reactive B cells using our proprietary Single B platform. | 1 – 2 Weeks |
| 3. VHH Library Generation | Construction of a comprehensive VHH library derived from the immunized camelid B cells. | 4 Weeks |
| 4. Screening & Identification | High-throughput screening to isolate and sequence VHH hits exhibiting high target specificity and affinity. | Within 2 Months |
| 5. Optimization (Optional) | Further engineering via mammalian cell display for enhanced affinity, solubility, or stability. | Upon Request |