AChE/BChE/MAO-B-IN-4

SKU: orb1744891

Description

AChE/BChE/MAO-B-IN-4, an indan-1-one derivative, is a potent inhibitor of monoamine oxidase B (MAO-B) and acetylcholinesterase/butyrylcholinesterase (AChE/BChE). It strongly inhibits human MAO-B with an IC50 of 0.0393 μM and is highly effective against human AChE and BChE with IC50 values of 0.0458 μM and 0.075 μM, respectively. Additionally, this compound exhibits significant antioxidant properties and ability to prevent β-amyloid plaque aggregation, suggesting its potential in Alzheimer's disease (AD) research.

Research Area

Neuroscience

Images & Validation

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Key Properties

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MW	451.56
Formula	C₂₆H₃₃N₃O₄
SMILES	CN(C)CCCN(C)CC(=O)NC1=CC=C(C=C1)/C=C\2/CC3=CC(=C(C=C3C2=O)OC)OC
Target	Others,Cholinesterase (ChE),Monoamine Oxidase

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

166642391 ↗

Key Properties

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No computed properties available.

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