Antibacterial agent 144

SKU: orb2278069

Description

Antibacterial Agent 144 (compound 8e) exhibits superior efficacy against multi-resistant Staphylococcus aureus compared to Chloromycin and Amoxicillin. It acts by disrupting the bacterial cytoplasmic membrane and inhibiting biofilm formation. Additionally, it binds to human serum albumin (HSA) with a dissociation constant (Kd) of 13.2 μM, enhancing its bactericidal activity. This compound also forms a supramolecular complex with DNA, thereby hindering DNA replication.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

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Key Properties

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MW	481.51
Formula	C₂₆H₂₃N₇O₃
Target	DNA/RNA Synthesis,Others,Antibacterial

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

DNA/RNA Synthesis,Others,Antibacterial

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