Biotin-PEG4-amine

SKU: orb1909505

Description

Biotin-PEG4-amine is a biotinylated PEGylated amine linker that provides a flexible spacer suitable for PROTAC synthesis and bioconjugation workflows. Biotin-PEG4-amine facilitates efficient ligand attachment to proteins or small molecules via its terminal amine while preserving accessibility for streptavidin-based detection or enrichment techniques.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	663171-32-2
MW	462.6
Purity	98.84%
Formula	C₂₀H₃₈N₄O₆S
SMILES	C(CCCC(NCCOCCOCCOCCOCCN)=O)[C@H]1[C@@]2([C@](CS1)(NC(=O)N2)[H])[H]
Target	PROTAC Linker
Solubility	DMSO:80 mg/mL (172.94 mM)

Bioactivity

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In Vitro	PROTACs comprise two ligands linked together: one binds an E3 ubiquitin ligase, and the other targets a specific protein. They harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins. Read more...

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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PEGs, Biotin PEG4 amine, BiotinPEG4amine, Biotin-PEG-4-amine, Biotin-PEG4-amine

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Compound Identifiers

PubChem CID

77078240 ↗

Key Properties

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No computed properties available.

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