CB1R antagonist 2

SKU: orb2944984

Description

CB1R antagonist 2 (Compound 11g) functions as an antagonist of the cannabinoid receptor 1 (CB1R), inhibiting the MAPK/NF-κB signaling pathway and exhibiting anti-inflammatory properties. In RAW264.7 cells, it suppresses LPS-induced expression of IL-6, IL-1β, and TNF-α. In murine models, it improves OVA-induced allergic rhinitis.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

−

Key Properties

−

MW	386.49
Formula	C₂₄H₂₆N₄O
Target	Cannabinoid Receptor,NF-κB,p38 MAPK

Storage & Handling

−

Storage	-20°C
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Quick Database Links

Gene Symbol

Cannabinoid Receptor,NF-κB,p38 MAPK

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols