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HIV-1 inhibitor-57

SKU: orb1944458

Description

HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50 values between 0.024 and 0.0010 μM. It achieves this efficacy by forming supplementary interactions with residues surrounding the binding site in the HIV-1 reverse transcriptase (RT).

Research Area

Infectious Disease & Virology, Protein Biochemistry

Images & Validation

Key Properties

CAS Number2745197-24-2
MW493.55
FormulaC25H24FN5O3S
SMILESFC1=C(C=CC(NC=2N=C(OC3=C(C)C=C(/C=C/C#N)C=C3C)C=CN2)=C1)N4CCS(=O)(=O)CC4
TargetHIV Protease,Others

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

HIV-1 inhibitor-57 (orb1944458)

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