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JE-133

SKU: orb2565922

Description

JE-133, an optically active isochromane-2H-chromene conjugate, displays both antioxidant and anti-inflammatory properties. As a neuroprotective agent, it effectively counters neuronal oxidative damage through modulation of the PI3K/Akt and MAPK signaling pathways. Additionally, JE-133 can suppress lipopolysaccharide (LPS)-induced neuroinflammation by influencing the JAK/STAT and Nrf2 signaling pathways.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number2579171-69-8
MW412.43
FormulaC23H24O7
SMILESC(OCC)(=O)[C@@H]1C(=CC=2C(O1)=CC=C(OC)C2)[C@H]3C=4C(C[C@@H](C)O3)=CC(O)=C(O)C4
TargetAkt,p38 MAPK,PI3K

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

JE-133 (orb2565922)

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