Men 10376 TFA(135306-85-3,free)

SKU: orb1296758

Description

Men 10376 TFA (135306-85-3, free) is a potent and selective neurokinin-2 (NK-2) receptor antagonist, exhibiting a Kᵢ of 4.4 nM in rat small intestine. It is a valuable research tool for investigating tachykinin signaling in gastrointestinal, pulmonary, and central nervous system disorders using in vitro and in vivo models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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Target	Neurokinin receptor
Molecular Weight	1195.25
Purity	99.22%
Formula	C₅₉H₆₉F₃N₁₂O₁₂
SMILES	CC([C@H](NC([C@H](NC([C@@H](NC([C@@H](N)CC(O)=O)=O)CC1=CC=C(O)C=C1)=O)CC2=CNC3=CC=CC=C32)=O)C(N[C@@H](C(N[C@@H](C(N[C@H](C(N)=O)CCCCN)=O)CC4=CNC5=CC=CC=C54)=O)CC6=CNC7=CC=CC=C76)=O)C.OC(C(F)(F)F)=O

Storage & Handling

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Storage	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Men 10376 TFA, Men 10376 TFA(135306 85 3,free), Men 10376 TFA(135306853,free), Men 10376 TFA(135306-85-3,free), NK2, Neurokinin-2 receptor antagonist TFA, Neurokininreceptor, Neurokinin receptor

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Compound Identifiers

PubChem CID

138319708 ↗

Key Properties

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No computed properties available.

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