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MRS5663

SKU: orb2646253

Description

MRS5663 (Compound 3a) is a potent and selective A3 adenosine receptor (A3AR) agonist with an EC50 of 5.62 nM in β-arrestin2 recruitment assays. It has demonstrated cytoprotective efficacy in preclinical models of skeletal muscle ischemia-reperfusion injury and claudication, supporting research in cardiovascular and metabolic diseases.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1377272-66-6
MW452.89
FormulaC22H21ClN6O3
SMILESC(NC)(=O)[C@]12[C@](C1)([C@H]([C@H](O)[C@@H]2O)N3C=4C(N=C3)=C(NC)N=C(C#CC5=C(Cl)C=CC=C5)N4)[H]
TargetAdenosine Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

MRS5663 (orb2646253)

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