Trimipramine maleate

SKU: orb1309950

Description

Trimipramine maleate is a tricyclic antidepressant salt that acts by inhibiting the reuptake of serotonin and norepinephrine, thereby potentiating their synaptic activity. It is utilized in neuroscience research for investigating monoamine neurotransmission in both in vitro binding assays and in vivo behavioral models of depression.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	521-78-8
MW	410.51
Purity	99.47% (May vary between batches)
Formula	C₂₄H₃₀N₂O₄
SMILES	OC(=O)\C=C/C(O)=O.CC(CN(C)C)CN1c2ccccc2CCc2ccccc12
Target	Adrenergic Receptor,Histamine Receptor,Antibacterial,5-HT Receptor,Dopamine Receptor,Norepinephrine
Solubility	DMSO:50 mg/mL (121.8 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.87 mM)

Bioactivity

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Target IC50	5-HT2 receptor:8.10 (pKi)\|5-HT1C receptor:6.39 (pKi)\|sPLA2:4.66 (pKi)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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dopamine, Dopamine, Dopamine Receptor, DopamineReceptor, DA D2 receptor, DA transporter, anxiolytic, antidepressants, Bacterial, 5-HTIA receptors, 5-HTlc receptors, 5-HT, 5HT Receptor, 5HTReceptor, 5-hydroxytryptamine, 5-hydroxytryptamine Receptor, AdrenergicReceptor, Adrenergic Receptor, 5-HT Receptor, 5-HT1A, 5-HT1C, 5-HT2, neurological disease, noradrenaline, Noradrenaline transporter (Sodium-dependent), inhibit, human organic cation transporters, H1 receptor, hNAT, hOCT1, hOCT2, hOCT3, hSERT, Inhibitor, hDAT, Histamine Receptor, HistamineReceptor, Surmontil maleate, Surmontil Maleate, Trimipramine, Trimipramine maleate, Trimipramine Maleate, Sert (Sodium-dependent), serotonin, Serotonin Receptor

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Compound Identifiers

PubChem CID

5282318 ↗

Key Properties

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No computed properties available.

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