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Riluzole

SKU: orb1310698

Description

Riluzole

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1744-22-5
MW234.2
Purity99.88%
FormulaC8H5F3N2OS
SMILESNC1=NC2=C(S1)C=C(OC(F)(F)F)C=C2
TargetSodium Channel,NMDAR,GABA Receptor
SolubilityDMSO:240 mg/mL (1024.77 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (21.35 mM);Ethanol:43 mg/mL (183.6 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

Target IC50
GABA:43 μM
In Vivo
Riluzole readily crosse the blood-brain barrier. Treatment of rodents with transient cerebral ischemia with 8 mg/kg i.p. Riluzole completely inhibite the massive release of glutamic acid induced by local ischemia.
In Vitro
Riluzole readily crosse the blood-brain barrier. Treatment of rodents with transient cerebral ischemia with 8 mg/kg i.p. Riluzole completely inhibite the massive release of glutamic acid induced by local ischemia.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

RP54274, RP-54274, RP 54274, Riluzole, Sodium Channel, SodiumChannel, PK 26124, PK26124, PK-26124, γ-Aminobutyric acid Receptor, Gamma-aminobutyric acid Receptor, GABAReceptor, GABA Receptor, GABA, Inhibitor, inhibit, NMDA receptor, Na+ channels, Na channels

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Quality Guarantee

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Key Properties

No computed properties available.

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Riluzole (orb1310698)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

25 mg
¥ 1,040.00
1 ml x 10 mM (in DMSO)
¥ 1,170.00
50 mg
¥ 1,170.00
100 mg
¥ 1,300.00
500 mg
¥ 2,080.00
1 g
¥ 2,600.00
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