Amivantamab (FUT8-KO) Antibody

SKU: orb2695768

Description

Amivantamab (FUT8-KO) is a humanized bispecific EGFR-MET antibody engineered with FUT8 knockout. Its Fc-enhanced mechanism blocks ligand binding, drives receptor degradation, and promotes Fc-dependent immune effector functions like ADCC and phagocytosis. This makes it a valuable tool for investigating targeted and immuno-oncology mechanisms in both in vitro and in vivo cancer models.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

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Key Properties

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Antibody Type	Inhibitor Antibody
Target	EGFR
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

3080731 ↗

Key Properties

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No computed properties available.

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