CD314 Antibody (PE)

SKU: orb154504

Description

Mouse monoclonal antibody conjugated to PE which recognizes CD314 that is also known as BAT221, NKG2D a cell surface receptor of the type II transmembrane receptor NKG2 family. CD314 is expressed on NK cells and some T cell subsets, where it functions as an activating receptor to trigger cytolytic activity and cytokine secretion.

Research Area

Epigenetics, Immunology

Images & Validation

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Item 1 of 1

Tested Applications	FC
Reactivity	Human
Application Notes	Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Key Properties

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Antibody Type	Primary Antibody
Clonality	Monoclonal
Isotype	Mouse IgG1 kappa
Clone No.	1D11
Immunogen	NKL cell line
Target	CD314
Purification	Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Conjugation	PE

Storage & Handling

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Storage	Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Buffer/Preservatives	Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Disclaimer	For research use only

Alternative Names

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NKG2D, KLRK1, KLR

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Flow cytometry analysis (surface staining) of human peripheral blood with anti-human CD314 (1D11) PE.

Quick Database Links

Gene Symbol

CD314

UniProt

P26718

NCBI Gene ID

22914

UniProt Details

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No UniProt data available

NCBI Gene Details

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No NCBI Gene data available

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Protocol Information

Flow Cytometry

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