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CL 316243 free acid

SKU: orb2646040

Description

CL 316243 free acid is a selective β3-adrenergic receptor agonist, demonstrating in vitro activity with IC50 values of 0.6 μM and 1 μM in rat heart and soleus muscle, respectively. It also potently inhibits spontaneous contractions in rat detrusor muscle strips (average IC50 = 2.65 nM), supporting its research use in studying smooth muscle physiology and metabolic disorders.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number183720-02-7
MW421.83
FormulaC20H20ClNO7
SMILESC(O)(=O)C1(C(O)=O)OC=2C(O1)=CC(C[C@H](NC[C@H](O)C3=CC(Cl)=CC=C3)C)=CC2
TargetAdrenergic Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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CL 316243 free acid (orb2646040)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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