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DBCO-PEG4-Val-Ala-PAB-PNP

SKU: orb3022081

Description

DBCO-PEG4-Val-Ala-PAB-PNP is a cleavable ADC linker. The Val-Ala dipeptide sequence can be cleaved by cathepsin B. The DBCO group is typically utilized in click chemistry reactions. The PEG spacer enhances the compound's solubility in water. PNP serves as an effective leaving group.

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Key Properties

CAS Number2348405-93-4
MW993.065
FormulaC52H60N6O14
SMILESC(CCC(NCCOCCOCCOCCOCCC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(OC2=CC=C(N(=O)=O)C=C2)=O)C=C1)=O)C)=O)[C@H](C)C)=O)=O)(=O)N3C=4C(C#CC=5C(C3)=CC=CC5)=CC=CC4
TargetADC Linker

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

DBCO-PEG4-Val-Ala-PAB-PNP (orb3022081)

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