Desethoxy Quetiapine hydrochloride

SKU: orb2283311

Description

Desethoxy quetiapine, an active metabolite of quetiapine formed by CYP3A5, acts as a dopamine D2 receptor antagonist (IC50 = 1,330 nM). It demonstrates in vivo efficacy by reducing apomorphine-induced climbing and improving swimming deficits in mice, supporting its use in researching dopamine-related behaviors and antipsychotic mechanisms.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	329218-14-6
MW	412.38
Formula	C₁₉H₂₁N₃OS?2HCl
SMILES	C(CO)N1CCN(C=2C=3C(SC=4C(N2)=CC=CC4)=CC=CC3)CC1.Cl
Target	Others,Dopamine Receptor

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

156593827 ↗

Key Properties

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No computed properties available.

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