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NF-κB Antibody

SKU: orb3131439

Description

PE0116 is a fully humanized CD137 agonistic monoclonal antibody, generated from immunized Harbor H2L2 transgenic mice. Acting as a ligand blocker, PE0116 activates NF-κB signaling, which significantly enhances T cell proliferation and increases cytokine secretion in vitro. In the MC38 tumor model, PE0116 demonstrates strong antitumor activity.

Images & Validation

Key Properties

Antibody TypeInhibitor Antibody
ClonalityMonoclonal
TargetNF-κB
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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NF-κB Antibody (orb3131439)

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