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Varenicline-d4 hydrochloride

SKU: orb3138522

Description

Varenicline-d4hydrochloride is a deuterium-labeled form of Varenicline (dihydrochloride). Varenicline (CP 526555) dihydrochloride acts as a partial agonist for the α4β2 nicotinic acetylcholine receptor (α4β2nAChR), with an EC50 of 2.3 μM. It serves as a full agonist for α3β4nAChR and α7nAChR, with EC50 values of 55 μM and 18 μM, respectively. As a nicotine ligand based on a cytosine structure, Varenicline dihydrochloride is utilized in smoking cessation research.

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Key Properties

TargetAChR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Varenicline-d4 hydrochloride (orb3138522)

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