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XEN907

SKU: orb1307600

Description

XEN907 is a novel spiro oxindole compound that potently blocks the NaV1.7 voltage-gated sodium channel, exhibiting an IC50 of 3 nM against the human isoform (hNaV1.7). This selective inhibitor is a valuable research tool for investigating pain pathways in both in vitro electrophysiology studies and in vivo preclinical models of nociception.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number912656-34-9
MW351.4
Purity99.92%
FormulaC21H21NO4
SMILESCCCCCN1C(=O)C2(COc3cc4OCOc4cc23)c2ccccc12
TargetSodium Channel,Others
SolubilityDMSO:60 mg/mL (170.75 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.69 mM)

Bioactivity

Target IC50
Nav1.7:3 nM (IC50)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

XEN 907, XEN907, XEN-907
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

XEN907 (orb1307600)

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Available Sizes

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2 mg
¥ 1,040.00
1 ml x 10 mM (in DMSO)
¥ 1,300.00
5 mg
¥ 1,300.00
10 mg
¥ 1,690.00
25 mg
¥ 2,470.00
50 mg
¥ 3,380.00
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