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ZG297

SKU: orb2945980

Description

ZG297 is a potent agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 µM. It exerts its antistaphylococcal activity by degrading SaFtsZ to inhibit cell division, showing efficacy against MRSA in vitro and demonstrating anti-infective properties in mouse infection models.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number2999673-52-6
MW568.63
FormulaC31H35F3N4O3
SMILESC(NCCCC(F)(F)F)(=O)N1[C@@]2(N([C@@]([C@H](CC)C)(C(=O)N(CC3=C4C(=C5C(=C3)C=CC=C5)C=CC=C4)C2)[H])C(=O)CC1)[H]
TargetAntibiotic,Antibacterial

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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ZG297 (orb2945980)

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