1-Aminocyclopropane-1-carboxylic acid

SKU: orb1302592

Description

1-Aminocyclopropane-1-carboxylic acid (ACC) is a dual-acting NMDA receptor modulator, serving as a glycine-site agonist at low glutamate and a glutamate-site antagonist at high glutamate. This unique profile underlies its neuroprotective effects in in vivo ischemia models, where it moderates receptor activity to prevent excitotoxicity. It is also a key biosynthetic precursor to the plant hormone ethylene.

Research Area

Metabolism Research, Neuroscience

Images & Validation

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Key Properties

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CAS Number	22059-21-8
MW	101.1
Purity	99.76%
Formula	C₄H₇NO₂
SMILES	NC1(CC1)C(O)=O
Target	NMDAR,Endogenous Metabolite
Solubility	DMSO:Insoluble;H2O:10 mM

Bioactivity

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Target IC50	NMDAR:0.7-0.9 µM (EC50)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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NMDA receptor, inhibit, EndogenousMetabolite, Inhibitor, 1-Amino-1-carboxycyclopropane, 1Aminocyclopropane1carboxylic acid, 1-Aminocyclopropane-1-carboxylic acid, 1-Aminocyclopropanecarboxylic acid, 1 Aminocyclopropane 1 carboxylic acid, ACC, Endogenous Metabolite

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Compound Identifiers

PubChem CID

535 ↗

Key Properties

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No computed properties available.

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