1-Phenylbiguanide HCl

SKU: orb2567339

Description

Compound PDK0269 is a 5-HT3 receptor agonist (pEC50 5.05±0.06) that modulates hypoglossal (XII) nerve burst patterns and evokes dopamine release, an effect blocked by nomifensine. This small molecule is a useful research tool for investigating serotonergic regulation of respiratory and dopaminergic systems in vitro.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	55-57-2
MW	213.67
Purity	98.00% (May vary between batches)
Formula	C₈H₁₂ClN₅
SMILES	Cl.N=C(N)NC(=N)NC=1C=CC=CC1
Target	5-HT Receptor

Bioactivity

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Target IC50	5-HT3 receptor:3 μM (EC50)

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Phenylbiguanide hydrochloride

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Compound Identifiers

PubChem CID

5932 ↗

Key Properties

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No computed properties available.

Protocol Information

Find More Protocols

Purity:	>98% (HPLC)
CAS Number:	55-57-2
MW:	213.67
Formula:	C₈H₁₂ClN₅

1-Phenylbiguanide HCl

Description

Research Area

Images & Validation

Key Properties

Bioactivity

Storage & Handling

Alternative Names

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