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15-deoxy-Δ12,14-Prostaglandin D2

SKU: orb2283607

Description

15-deoxy-Δ¹²,¹⁴-PGD2 is a potent DP2 receptor agonist (Ki=50 nM) that activates eosinophils (EC50=8 nM) and modulates PPARγ transcription. It demonstrates cytotoxic effects on leukemia cells and inhibits platelet aggregation. This metabolite is a valuable tool for researching allergic inflammation, cancer biology, and cardiovascular function in both cellular and animal models.

Research Area

Cardiovascular Research, Immunology & Inflammation, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number85235-11-6
MW334.456
FormulaC20H30O4
SMILESCCCCC\C=C\C=C1/[C@@H](C\C=C/CCCC(O)=O)[C@@H](O)CC1=O
TargetOthers,Src,Endogenous Metabolite,Prostaglandin Receptor,PPAR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information

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500 μg
$ 270.00
1 mg
$ 480.00
DispatchUsually dispatched within 5-10 working days
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