15-deoxy-Δ12,14-Prostaglandin D2

SKU: orb2283607

Description

15-deoxy-Δ¹²,¹⁴-PGD2 is a potent DP2 receptor agonist (Ki=50 nM) that activates eosinophils (EC50=8 nM) and modulates PPARγ transcription. It demonstrates cytotoxic effects on leukemia cells and inhibits platelet aggregation. This metabolite is a valuable tool for researching allergic inflammation, cancer biology, and cardiovascular function in both cellular and animal models.

Research Area

Cardiovascular Research, Immunology & Inflammation, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	85235-11-6
MW	334.456
Formula	C₂₀H₃₀O₄
SMILES	CCCCC\C=C\C=C1/[C@@H](C\C=C/CCCC(O)=O)[C@@H](O)CC1=O
Target	Src,Endogenous Metabolite,Prostaglandin Receptor,PPAR,Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

5283052 ↗

Key Properties

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No computed properties available.

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