17-Demethoxy-reblastatin

SKU: orb2665463

Description

17-Demethoxy-reblastatin (17-DR) is an Hsp90 inhibitor that demonstrates anti-cancer activity in vitro by inhibiting proliferation and colony formation in HepG2 and SMMC7721 cells. It induces apoptosis through a mitochondrial and caspase-dependent pathway, making it a useful tool for oncology and molecular chaperone research.

Research Area

Cell Biology, Metabolism Research, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	299173-64-1
MW	518.64
Formula	C₂₈H₄₂N₂O₇
SMILES	CO[C@H]1CC\C=C(C)/C(=O)NC2=CC(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)\C=C(C)\[C@H]1OC(N)=O)=CC(O)=C2
Target	HSP,Apoptosis

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

176419166 ↗

Key Properties

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No computed properties available.

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