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(1S,2S)-ML-SI3

SKU: orb2567310

Description

(1S,2S)-ML-SI3 is the (-)-trans-isomer and a potent TRPML1/2 inhibitor, with weaker activity against TRPML3. Its (+)-enantiomer conversely inhibits TRPML1 but activates TRPML2/3. This stereospecific modulation makes it a valuable chemical tool for studying lysosomal ion channel function in cellular and biochemical assays.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2563870-87-9
MW429.58
FormulaC23H31N3O3S
SMILESN(S(=O)(=O)C1=CC=CC=C1)[C@@H]2[C@H](CCCC2)N3CCN(CC3)C4=C(OC)C=CC=C4
TargetTRP/TRPV Channel

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information