(1S,3R,5R)-PIM447 dihydrochloride

SKU: orb1708151

Description

(1S,3R,5R)-PIM447 dihydrochloride is a pan-PIM kinase inhibitor with IC50 values of 0.095 µM, 0.522 µM, and 0.369 µM for Pim1, Pim2, and Pim3, respectively. This compound is a research tool for studying oncology and hematology, with applications in both in vitro biochemical assays and in vivo models of cancer.

Research Area

Cell Biology, Epigenetics & Chromatin, Signal Transduction

Images & Validation

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Key Properties

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MW	513.38
Formula	C₂₄H₂₅Cl₂F₃N₄O
SMILES	O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=C([C@@H]4C[C@H](N)C[C@H](C)C4)C=CN=C3.Cl.Cl
Target	CDK,Pim

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

124201617 ↗

Key Properties

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No computed properties available.

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