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2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan

SKU: orb2944953

Description

This research compound is a drug-linker conjugate featuring the topoisomerase I inhibitor Exatecan, designed for constructing antibody-drug conjugates (ADCs). It is utilized in preclinical studies for evaluating ADC efficacy and stability in both in vitro and in vivo cancer research models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2813269-48-4
MW1107.58
FormulaC53H55ClN10O13S
SMILESN(C(COCNC(CNC([C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCCC#CC=2C=NC(S(C)(=O)=O)=NC2)=O)=O)=O)=O)=O)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(Cl)C8
TargetDrug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information