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β2AR/M-receptor agonist-1

SKU: orb1982697

Description

β2AR/M-receptor agonist-1 (Example 131) is a dual-acting MABA compound with potent β2 adrenoceptor agonist (EC50 = 9.2 nM) and muscarinic receptor antagonist (Ki = 30.2 nM) activity. It is a valuable research tool for investigating bronchodilation mechanisms in respiratory disease models, both in vitro and in vivo.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2230520-62-2
MW806.82
FormulaC43H56BrN3O7
SMILES[Br-].O[C@H](CNCCCOc1ccc(OCCC[N+]23CCC(CC2)[C@@H](C3)OC[C@@](O)(C2CCCC2)c2ccccc2)cc1)c1ccc(O)c2[nH]c(=O)ccc12
TargetOthers,Adrenergic Receptor,AChR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

β2AR/M-receptor agonist-1 (orb1982697)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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