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(3S,4R)-Tofacitinib

SKU: orb1708148

Description

(3S,4R)-Tofacitinib is the less active enantiomer of the JAK3 inhibitor Tofacitinib (IC50 = 1 nM). This compound is used as a comparative control in biochemical and cellular assays to study JAK-STAT signaling pathways in immunological and inflammatory disease research.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1092578-48-7
MW312.37
FormulaC16H20N6O
SMILESC[C@@H]1CCN(C[C@H]1N(C)c1ncnc2[nH]ccc12)C(=O)CC#N
TargetOthers,JAK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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25 mg
$ 1,860.00
50 mg
$ 2,420.00
100 mg
$ 3,140.00
DispatchUsually dispatched within 5-10 working days
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