4-Methylbenzylidene camphor

SKU: orb1299797

Description

4-Methylbenzylidene camphor (4-MBC) is a synthetic UV-B filter used in sunscreens. It is employed in research to study its endocrine-disrupting potential, particularly its estrogenic activity, in both in vitro receptor assays and in vivo toxicological models.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	36861-47-9
MW	254.37
Purity	99.59% (May vary between batches)
Formula	C₁₈H₂₂O
SMILES	Cc1ccc(\C=C2\C3CCC(C)(C2=O)C3(C)C)cc1
Target	Akt,ERK,Cholinesterase (ChE),PI3K,Apoptosis
Solubility	DMSO:18.33 mg/mL (72.06 mM);10% DMSO+90% Corn Oil:1.5 mg/mL (5.9 mM)

Bioactivity

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In Vivo	4-Methylbenzylidene camphor has estrogenic activity in fish and in mammals, binding competitively to estrogen receptors and stimulating transactivation.In addition to reducing receptor sensitivity to estradiol, 4-MBC directs dose-dependent changes in the expression of estrogen receptor subtypes, progesterone receptor, and androgen receptor Read more...

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Inhibitor, inhibit, Enzacamene, Cholinesterase (ChE), 4-MBC, 4Methylbenzylidene camphor, 4-Methylbenzylidene camphor, 4 Methylbenzylidene camphor, AChE

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Compound Identifiers

PubChem CID

6440721 ↗

Key Properties

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No computed properties available.

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