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5-HT1AR agonist 2

SKU: orb2802344

Description

Compound 4f is a potent 5-HT1A receptor agonist (Ki=10.0 nM) with additional affinity for SERT, D2, and 5-HT6 receptors. Its metabolic stability and in vivo hypothermic effect in mice support its utility for neuropsychiatric research, including studies of serotonin and dopamine systems in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

MW521.61
FormulaC31H31N5O3
TargetInterleukin,5-HT Receptor,NOD-like Receptor (NLR),RIP kinase,Serotonin Transporter,Dopamine Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information