Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

5-LOX inhibitor

SKU: orb1962274

Description

This compound, 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one, is a 5-lipoxygenase (5-LOX) inhibitor identified as a process-related impurity of itraconazole. It serves as a research tool for investigating the 5-LOX pathway in leukotriene biosynthesis during in vitro enzymatic and cellular assays.

Research Area

Metabolism Research, Metabolism Research; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number106461-41-0
MW393.48
Purity98.01% (May vary between batches)
FormulaC22H27N5O2
SMILESCCC(C)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(O)cc2)c1=O
TargetHedgehog/Smoothened,Lipoxygenase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

5-LOX, 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one

Similar Products

  • Xanthine dehydrogenase Inhibitor 1 [orb1302208]

    95.00% (May vary between batches)

    80025-67-8

    252.2

    C11H7F3N4

    5 mg, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO), 200 mg
  • Psoralidin [orb1304238]

    98.00% (May vary between batches)

    18642-23-4

    336.34

    C20H16O5

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO), 200 mg, 2 mg
  • Licofelone [orb1300651]

    99.25% (May vary between batches)

    156897-06-2

    379.88

    C23H22ClNO2

    10 mg, 25 mg, 50 mg, 100 mg, 500 mg, 200 mg, 5 mg, 1 ml x 10 mM (in DMSO)
  • Pectolinarigenin [orb1300253]

    98.67% (May vary between batches)

    520-12-7

    314.29

    C17H14O6

    5 mg, 25 mg, 50 mg, 100 mg, 10 mg, 1 ml x 10 mM (in DMSO), 1 mg
  • Phenethyl ferulate [orb1297170]

    99.58% (May vary between batches)

    71835-85-3

    298.33

    C18H18O4

    1 mg, 5 mg, 10 mg, 50 mg, 25 mg, 100 mg, 1 ml x 10 mM (in DMSO)
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

5-LOX inhibitor (orb1962274)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

5 mg
¥ 1,040.00
10 mg
¥ 1,300.00
25 mg
¥ 1,690.00
50 mg
¥ 2,210.00
100 mg
¥ 2,990.00
500 mg
¥ 6,760.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry