6'-GNTI dihydrochloride

SKU: orb1690916

Description

6'-GNTI dihydrochloride is a G-protein-biased κ-opioid receptor (KOR) agonist that selectively activates the Akt pathway in striatal neurons. This compound is a valuable research tool for investigating biased KOR signaling in vitro and studying neuropsychiatric disorders, including addiction and depression, in preclinical models.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	2410327-94-3
MW	544.47
Purity	99.54%
Formula	C₂₇H₂₉N₅O₃.2ClH
SMILES	O[C@]12[C@]34[C@](OC5=C(O)C=CC(C[C@@]2([H])N(CC4)CC6CC6)=C53)([H])C7=C(C8=CC=C(NC(N)=N)C=C8N7)C1.Cl.Cl
Target	Akt,Opioid Receptor
Solubility	DMSO:10.42 mg/mL (19.14 mM)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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OpioidReceptor, Opioid Receptor, 6'-GNTI, 6'GNTI dihydrochloride, 6'-GNTI Dihydrochloride, 6' GNTI dihydrochloride, Akt, κ-opioid receptor

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Compound Identifiers

PubChem CID

146673012 ↗

Key Properties

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No computed properties available.

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