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7-keto-25-hydroxy Cholesterol

SKU: orb2283011

Description

This oxysterol metabolite of 7-keto and 7-dehydro cholesterol is a Smoothened (Smo) agonist, binding to its extracellular cysteine-rich domain. It also modulates EGF receptor affinity in NRK cells, making it a valuable tool for studying Hedgehog signaling and receptor biology in vitro.

Research Area

Metabolism Research, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number64907-23-9
MW416.646
FormulaC27H44O3
SMILESC[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@]12C)[C@@]1(C)CC[C@H](O)CC1=CC3=O
TargetSmo,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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500 μg
$ 320.00
1 mg
$ 540.00
5 mg
$ 1,820.00
DispatchUsually dispatched within 5-10 working days
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