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A-1155905

SKU: orb2665558

Description

A-1155905 is a potent and selective MCL-1 inhibitor with an IC50 of 33.5 nM and a Ki of 0.58 nM. It disrupts the MCL-1/Bim interaction, inducing caspase-dependent apoptosis in MCL-1-dependent cancer cells in vitro, making it a valuable tool for oncology research targeting apoptotic pathways.

Research Area

Cell Biology, Protein Biochemistry

Images & Validation

Key Properties

CAS Number2228052-37-5
MW802.93
FormulaC46H51FN6O6
SMILESO=C(O)C1=C(C=2C=CC=C(C=3C(=NN(C3COC4=CC=C(C=C4)N5CCN(C(=O)C)CC5)C)C)C2N1CCN6CCOCC6)CCCOC7=CC=CC=8C(F)=CC=CC78
TargetApoptosis,Caspase,Bcl-2 Family

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

A-1155905 (orb2665558)

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