A3AR agonist 2

Compound 19 is a potent and selective A3 adenosine receptor agonist (K i = 22.1 nM) that promotes β-arrestin2 recruitment (EC 50 = 4.36 nM). It is a valuable research tool for studying A3AR function in models of inflammation, ischemia, neuropathic pain, cancer, and liver disease, supporting both in vitro and in vivo experimental applications.