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AAK1/HDACs-IN-1

SKU: orb2814418

Description

AAK1/HDACs-IN-1 (Compound 12) is a potent dual inhibitor of AAK1, HDAC1, and HDAC6 with IC50 values of 15.9, 148.6, and 5.2 nM, respectively. It has demonstrated antiviral activity in vitro by inhibiting SARS-CoV-2 entry through disruption of clathrin-mediated endocytosis, making it a useful research tool for studying viral infection pathways and epigenetic regulation.

Research Area

Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology, Neuroscience

Images & Validation

Key Properties

MW354.36
FormulaC21H14N4O2
TargetHDAC,AAK1 (AP2 associated kinase 1),SARS-CoV

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information