AC-099 hydrochloride

SKU: orb1941559

Description

AC-099 hydrochloride is a small molecule acting as a selective, full agonist at the NPFF2 receptor (EC50=1189 nM) and a partial agonist at NPFF1R (EC50=2370 nM). It is applied in research to reverse opioid-induced hyperalgesia and is utilized in both in vitro receptor studies and in vivo models of nociceptive sensitization and opioid tolerance.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	849335-07-5
MW	301.1
Purity	99.86%
Formula	C₉H₉Cl₂F₃N₄
SMILES	Cl.FC(F)(F)C1=CC(C=NNC(=N)N)=CC=C1Cl
Target	Others,Neuropeptide FF Receptor

Bioactivity

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In Vivo	The NPFF2 agonist AC-099 (30 mg/kg; i.p.) exhibits activity in various pain models in vivo, whereas non-selective NPFF1 agonist administration increases sensitivity to both noxious and non-noxious stimuli. Read more...

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Neuropeptide Y Receptor, NeuropeptideYReceptor, NPFFR2

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Compound Identifiers

PubChem CID

69536894 ↗

Key Properties

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No computed properties available.

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