(±)-Acetylcarnitine chloride

SKU: orb2283877

Description

Acetyl dl-carnitine chloride is a racemic mixture acting as a mild cholinergic agonist with demonstrated neuroprotective effects. It is utilized in research models of neuritis and neurodegenerative diseases, with applications in both in vitro cellular studies and in vivo animal experiments investigating neuroinflammation and mitochondrial function.

Research Area

Neuroscience

Images & Validation

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Key Properties

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CAS Number	2504-11-2
MW	239.7
Purity	99.98%
Formula	C₉H₁₈ClNO₄
SMILES	[Cl-].O=C(OC(CC(=O)O)C[N+](C)(C)C)C
Target	Cholinesterase (ChE),AChR
Solubility	H2O:80 mg/mL (333.75 mM)

Bioactivity

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In Vivo	In rats, infusion of 2 mg of (±)-acetylcarnitine chloride reduced hindlimb blood flow by 50%. (±)-Acetylcarnitine chloride also potentiated the inhibitory effect of adrenaline on isolated rabbit duodenum. Read more...
In Vitro	(±)-Acetylcarnitine chloride increase significantly during fly flight, and acetylcarnitine transferase is active, indicating that acetylcarnitine plays an important role in carbohydrate metabolism. Acetylcarnitine is synthesized by the choline acetylase system isolated from brain tissue and is broken down by cholinesterase. Read more...

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Cholinergic, (±) Acetylcarnitine chloride, (±)Acetylcarnitine chloride, Acetyl dl-carnitine chloride

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Compound Identifiers

PubChem CID

197763 ↗

Key Properties

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No computed properties available.

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