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AD186

SKU: orb2278309

Description

AD186 is a potent and selective sigma-1 receptor (S1R) agonist with high affinity (Ki = 2.7 nM) and 10-fold selectivity over the sigma-2 receptor. It serves as a valuable pharmacological tool for investigating S1R function in neuropathic pain models, as evidenced by its ability to reverse the antiallodynic effects of BD-1063 in vivo.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW320.47
FormulaC22H28N2
TargetSigma receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information