Adenosine 5'-diphosphate

SKU: orb1307617

Description

Adenosine 5'-diphosphate (ADP) is a key nucleotide metabolite formed from ATP hydrolysis. It is crucial for energy transfer in cellular metabolism and is a primary agonist for platelet activation studies. This makes it essential for in vitro research in biochemistry, cell signaling, and hemostasis/thrombosis models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	58-64-0
MW	427.2
Purity	98.07% (May vary between batches)
Formula	C₁₀H₁₅N₅O₁₀P₂
SMILES	O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(=O)(O)O)(=O)O)[C@H]1O
Target	Endogenous Metabolite
Solubility	H2O:100 mg/mL (234.08 mM);DMSO:14 mM

Bioactivity

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Target IC50	P2X2/3:67 nM\|P2Y1:24 nM (EC50)
In Vivo	METHODS: To investigate the role in tissue repair, Adenosine 5'-diphosphate (15.2 µg/kg) was applied topically to diabetic mice in a total excisional wound model once daily for 14 days. RESULTS: Adenosine 5'-diphosphate accelerated cutaneous wound healing, improved new tissue formation, and increased collagen deposition and TGF-β production in the wounds.Adenosine 5'-diphosphate acts as a pro-absorptive mediator in diabetes-related cutaneous wounds.
In Vitro	METHODS: Fibroblast-like synoviocytes FLS1 were treated with Adenosine 5'-diphosphate (100 µM) for 24 h, and gene expression levels were measured by RT-qPCR. RESULTS: MCP-1/CCL-2 mRNA expression was up-regulated 2.31-fold in FLS1 cells treated with Adenosine 5'-diphosphate (100 µM).

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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ADP, adenosine Pyrophosphate, adenosine pyrophosphate, Adenosine Diphosphate, Adenosine diphosphate, Adenosine 5' diphosphate, Adenosine 5'diphosphate, Adenosine 5'-diphosphate, Adenosine, Inhibitor, EndogenousMetabolite, Endogenous Metabolite, inhibit

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Compound Identifiers

PubChem CID

6022 ↗

Key Properties

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No computed properties available.

Protocol Information

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Purity:	≥ 95% (HPLC)
CAS Number:	40811-89-0
MW:	Theoretical MW: 517.33 g/mol (free acid); Detected MW: 517.08 g/mol (free acid)
Formula:	C₁₇H₂₁N₅O₁₀P₂

Purity:	≥ 95% (HPLC)
MW:	Theoretical MW: 871.60 g/mol (free acid); Detected MW: 871.13 g/mol (free acid)
Formula:	C₃₄H₃₁N₇O₁₇P₂

Purity:	≥ 95% (HPLC)
MW:	Theoretical MW: 871.60 g/mol (free acid); Detected MW: 871.13 g/mol (free acid)
Formula:	C₃₄H₃₁N₇O₁₇P₂

Purity:	≥ 95% (HPLC)
MW:	Theoretical MW: 999.07 g/mol (free acid)
Formula:	C₃₆H₃₃Cl₂N₇O₁₉P₂

Purity:	≥ 95% (HPLC)
MW:	Theoretical MW: 925.74 g/mol (free acid); Detected MW: 925.22 g/mol (free acid)
Formula:	C₃₈H₄₁N₉O₁₅P₂

Adenosine 5'-diphosphate

Description

Research Area

Images & Validation

Key Properties

Bioactivity

Storage & Handling

Alternative Names

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