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AER-271

SKU: orb1299360

Description

AER-271

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number634913-39-6
MW463.65
Purity99.03%
FormulaC15H9ClF6NO5P
SMILESN(C(=O)C1=C(OP(=O)(O)O)C=CC(Cl)=C1)C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2
TargetAquaporin
SolubilityDMSO:27.5 mg/mL (59.31 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.31 mM)

Bioactivity

In Vivo
Treatment with AER-271 ameliorated early cerebral edema measured at 3 h after CA vs vehicle treated rats. This treatment also attenuated early NDS. In contrast to rats treated with vehicle after CA, rats treated with AER-271 did not develop significant neuronal death or neuroinflammation as compared to sham.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CNS, AQP4, aquaporin-4, acute, AER 271, AER-270, AER271, AER-271, injury, ischemic, inhibit, Inhibitor, stroke

Similar Products

  • AER-271 [orb1941024]

    >98% (HPLC)

    634913-39-6

    463.7

    C15H9ClF6NO5P

    25 mg, 2 mg, 5 mg, 10 mg, 50 mg, 100 mg, 1 g, 500 mg, 200 mg
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Key Properties

No computed properties available.

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Protocol Information

AER-271 (orb1299360)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

2 mg
¥ 1,040.00
5 mg
¥ 1,300.00
1 ml x 10 mM (in DMSO)
¥ 1,430.00
10 mg
¥ 1,950.00
25 mg
¥ 3,510.00
50 mg
¥ 5,070.00
100 mg
¥ 7,280.00
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