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ALC-0366

SKU: orb1910463

Description

ALC 0366 is an ionizable cationic lipid (pKa = 6.25) from Biontech,which is derived from ALC-0315. ALC0366 has been used as a key component of LNP to deliver BNT142, a lipid nanoparticle (LNP)-formulated RNA (RNA-LNP) encoding a T cell-engaging bispecific antibody that monovalently binds the T cell marker CD3 and bivalently binds claudin 6 (CLDN6), an oncofetal antigen that is absent from normal adult tissue but expressed on various solid tumors.

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Key Properties

CAS Number2096984-25-5
MW724.2
Purity>95%
FormulaC45H89NO5
SMILESOCCCN(CCCCCCCCCOC(C(CCCC)CCCCCC)=O)CCCCCCCCCOC(C(CCCC)CCCCCC)=O

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

ALC-0366 (orb1910463)

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100 mg
25 mg
¥ 5,070.00
50 mg
¥ 7,540.00