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Alendronate sodium

SKU: orb1704699

Description

This small molecule is a potent inhibitor of human farnesyl diphosphate synthase (FPPS; IC50 = 460 nM), a key enzyme in the mevalonate pathway. It induces macrophage apoptosis and disrupts protein prenylation and sterol biosynthesis in osteoclasts, making it a valuable research tool for studying bone resorption, immune cell biology, and metabolic disorders in cellular models.

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Key Properties

CAS Number129318-43-0
MW272.09
FormulaC4H13NNaO7P2
SMILES[Na].O=P(O)(O)C(O)(CCCN)P(=O)(O)O
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Alendronate sodium (orb1704699)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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