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Altenusin

SKU: orb1298545

Description

Altenusin is a fungal metabolite that acts as a selective FXR agonist with an EC50 of 3.2 µM. This small molecule is a valuable research tool for investigating FXR-related pathways in metabolic and liver diseases, applicable in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number31186-12-6
MW290.27
Purity99.87% (May vary between batches)
FormulaC15H14O6
SMILESC(O)(=O)C1=C(C=C(OC)C=C1O)C2=C(C)C=C(O)C(O)=C2
TargetFXR
SolubilityDMSO:50 mg/mL (172.25 mM)

Bioactivity

Target IC50
FXR:EC50 : 3.2 ± 0.2 μM
In Vitro
Treatment of primary mouse hepatocytes with altenusin inhibited oleic acid–induced steatosis in vitro .

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Altenusin, Alutenusin, inhibit, Inhibitor, FXR

Similar Products

  • Altenusin [orb1218182]

    >98% (HPLC)

    31186-12-6

    290.3

    C15H14O6

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 g, 500 mg
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Key Properties

No computed properties available.

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Altenusin (orb1298545)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 mg
¥ 5,590.00
5 mg
¥ 13,130.00
10 mg
¥ 17,290.00
25 mg
¥ 21,580.00
50 mg
¥ 33,020.00
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